Origin
Clayton, NC
Night in Clayton on Thursday
Local time
11:57 PM
EDT
Current temp
49°F
Unavailable
Last recalculated Apr 17, 2026
Drive Time
2h 25m
Distance
120.6 mi
194 km
Drive Score
8/10
Great drive
Same Day?
Yes, doable
Fuel Cost
$19
one way
EV Charging
Unknown
Estimated drive times based on typical traffic patterns. Actual times may vary with weather, construction, and real-time conditions.
Clayton, NC
Wikimedia Commons
This 120.6-mile drive from Clayton, NC, to Winston-Salem, NC, is a manageable one-day trip, taking about 2 hours and 25 minutes. You'll primarily use the Dan K Moore Freeway and I-40, with a short section on Salem Parkway, making it a 96% highway-focused journey. With an estimated fuel cost of $19, this route is budget-friendly for a day excursion. The drive is straightforward, designed for efficient travel between these two North Carolina locations within the Southeast region. It's a perfect length for a single-day adventure, allowing you to reach your destination without needing an overnight stay.
Trip Pace
Same-day drive is realistic
A same-day return is realistic if you keep stops short.
Midpoint
60.3 miles from Clayton, NC
A natural place for your longest stop of the day , about 1h 13m into the drive .
Weekend Trip
Doable as a same-day drive at 2h 25m. Total distance: 120.6 miles.
Family Friendly
Moderate complexity with 0 natural rest stops along the way.
Solo Traveler
2h 25m drive, comfortable solo distance.
First-Time Driver
Mostly highway driving (96%). Some complex stretches to watch for.
Expect a predominantly highway-focused experience on this route, with 96% of the journey on major freeways. The longest uninterrupted stretch you'll encounter is 69.7 miles along the Dan K Moore Freeway. This means you'll be on high-speed roads for the majority of the drive, offering a consistent pace. While not a winding, scenic byway, the efficiency of the interstate system allows for smooth and direct travel between Clayton and Winston-Salem. The character is largely about covering distance effectively on well-maintained roads.
This is a straightforward highway drive that stays mostly on Dan K Moore Freeway and I 40. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 0.5 miles in near Barbour Street.
Demanding - plan breaks and stay ahead of the key maneuvers
Balances navigation complexity with total wheel time.
This is a demanding drive. With 9 significant decision points across 120.6 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
Where does it get tricky?
The main spots that need attention: at 0.5 miles (Barbour Street): Navigation decision point; at 86.3 miles (I 40): Highway fork - watch signs carefully. Lane positioning matters here; at 94 miles (I 40; US 220): Highway fork - watch signs carefully. Lane positioning matters here.
These are the spots where you need to pay the most attention. Preview them before you drive.
Turn left onto Barbour Street
Navigation decision point
Keep slight right at fork onto I 40
Highway fork - watch signs carefully. Lane positioning matters here
Keep slight right at fork onto I 40; US 220
Highway fork - watch signs carefully. Lane positioning matters here
Keep slight right at fork onto US 421 / Salem Parkway toward US 421 North: Kernersville
Highway fork - watch signs carefully. Lane positioning matters here
Take the exit toward Main Street
Exit ramp - move to the correct lane early. Lane positioning matters here
| Road | Distance | Duration |
|---|---|---|
| Dan K Moore Freeway | 69.7 mi | 1h 20m |
| I 40 | 20.3 mi | 24m |
| Salem Parkway | 13.4 mi | 16m |
| Thomas Bradshaw Freeway | 8.5 mi | 9m |
| US 70 | 4.3 mi | 5m |
| Clayton Boulevard | 2.4 mi | 3m |
| South Main Street | 0.4 mi | <1m |
| North Lombard Street | 0.4 mi | 1m |
Step-by-step road directions between Clayton, NC and Winston-Salem, NC.
Start on North Lombard Street
Turn right onto Hamby Street
Turn left onto Barbour Street
Turn straight onto US 70
Continue on US 70
Take the ramp
Merge onto I 40
Continue on I 40; US 64
Continue on I 40; US 64
Continue on I 40; US 64
Keep slight right at fork onto I 40
Keep slight right at fork onto I 40; US 220
Keep slight right at fork onto US 421
Take the exit
Turn slight right onto South Main Street
Arrive at destination
Given the 2 hour and 25-minute duration and 120.6-mile distance, this trip is best suited for a single day, with no need to split it. Consider an early morning departure to avoid any potential traffic, especially as you approach Winston-Salem. While there are no designated stops in the data, plan for a brief break around the halfway point to stretch your legs. Keep an eye on your fuel; the estimated cost is $19, so you should have ample range, but it's always wise to top off before embarking. A specific tip for this route: be aware that the Dan K Moore Freeway eventually merges into I-40, so stay alert for lane changes as you transition.
Morning Departure
Leave by 9 AM and you'll arrive before lunch.
Evening Departure
Even a 4 PM departure gets you there before dark in summer.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 27 miles or 35m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 60.3 miles or 1h 13m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 1h 59m
Traffic, exits, and arrival timing usually matter more near Winston-Salem, NC than in the middle of the route.
Open the route before leaving Clayton, NC so your first major turns are already loaded.
Leave with enough water and a charging cable within reach, not packed away.
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from Clayton, NC
This is one driving day of about 120.6 miles and 2h 25m.
Rest stops, refuel points, and overnight suggestions along this route.
Halfway Point
Midpoint
About 60.3 mi from Clayton, NC · 1h 13m into the drive
Mid-route town
Meal stop
60 mi into the route
Best for: Lunch, fuel, and a longer reset
This sits close to the middle of the route, so it works well for the longest stop of the day.
A short stop after about 27 miles helps settle the day before fatigue starts building.
The midpoint is around 60.3 miles from Clayton, NC, which is a good place for a longer meal and fuel stop.
Before the longest stretch
Fuel checkTop up before Dan K Moore Freeway if your tank is already low. That segment runs about 69.7 miles.
The final approach into Winston-Salem, NC usually feels slower than the middle of the drive, so avoid planning your tightest schedule at the very end.
Try to arrive with enough fuel left to skip an immediate station stop unless you already know the area around Winston-Salem, NC.
These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.
Regular Gas
$18.86 one way
$37.72 round trip
| Fuel Type | $/gal | One Way | Round Trip |
|---|---|---|---|
| midgrade | $4.34 | $20.62 | $41.24 |
| premium | $4.70 | $22.32 | $44.64 |
| diesel | $5.61 | $26.63 | $53.25 |
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$19
Meals
$25–$50
Total
$44–$69
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 42.2 kg one way. Prices: EIA weekly data, 2026-04-13.
Driving Electric?
About $13 in charging · 0 stops · 67% less CO2
| Vehicle Type | kWh | Stops | DC Fast | Home Charge |
|---|---|---|---|---|
| Average EV | 36.2 | 0 | $12.66 | $5.79 |
| Efficient EV | 30.2 | 0 | $10.55 | $4.82 |
| EV Truck/SUV | 48.2 | 0 | $16.88 | $7.72 |
Gas CO2
42 kg
EV CO2
14 kg (67% less)
This trip is well within single-charge range for most EVs. No charging stops needed if you start fully charged.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Current conditions at both ends of the drive.
Origin
Night in Clayton on Thursday
Local time
11:57 PM
EDT
Current temp
49°F
Unavailable
Destination
Night in Winston-Salem on Thursday
Local time
11:57 PM
EDT
Current temp
42°F
Unavailable
50°F
Hillsborough, NC
60 mi in
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
Use the two city cards together: check the sky where you start, then compare it with the local time and temperature at arrival.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
Was this helpful?
Thanks for your feedback!
Your tip has been submitted. Thanks!
/500
Recent Tips
·
Explore more options from Clayton, NC or browse trips ending in Winston-Salem, NC.
Looking for more statewide routes? Browse NC road trips.