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Trip from Clayton, NC to Winston-Salem, NC

Last recalculated Apr 17, 2026

Drive Time

2h 25m

Distance

120.6 mi

194 km

Drive Score

8/10

Great drive

Same Day?

Yes, doable

Fuel Cost

$19

one way

EV Charging

Unknown

Best Time to Leave

Save up to 30 min
4 AM
2h 16m ★
6 AM
2h 26m
8 AM
2h 46m
10 AM
2h 33m
12 PM
2h 31m
3 PM
2h 34m
5 PM
2h 45m
8 PM
2h 20m

Estimated drive times based on typical traffic patterns. Actual times may vary with weather, construction, and real-time conditions.

town in North Carolina

Clayton, NC

Wikimedia Commons

Trip Overview

This 120.6-mile drive from Clayton, NC, to Winston-Salem, NC, is a manageable one-day trip, taking about 2 hours and 25 minutes. You'll primarily use the Dan K Moore Freeway and I-40, with a short section on Salem Parkway, making it a 96% highway-focused journey. With an estimated fuel cost of $19, this route is budget-friendly for a day excursion. The drive is straightforward, designed for efficient travel between these two North Carolina locations within the Southeast region. It's a perfect length for a single-day adventure, allowing you to reach your destination without needing an overnight stay.

Trip Pace

Same-day drive is realistic

A same-day return is realistic if you keep stops short.

Midpoint

60.3 miles from Clayton, NC

A natural place for your longest stop of the day , about 1h 13m into the drive .

Who Is This Route For?

Weekend Trip

Doable as a same-day drive at 2h 25m. Total distance: 120.6 miles.

Family Friendly

Moderate complexity with 0 natural rest stops along the way.

Solo Traveler

2h 25m drive, comfortable solo distance.

First-Time Driver

Mostly highway driving (96%). Some complex stretches to watch for.

Drive Character

Expect a predominantly highway-focused experience on this route, with 96% of the journey on major freeways. The longest uninterrupted stretch you'll encounter is 69.7 miles along the Dan K Moore Freeway. This means you'll be on high-speed roads for the majority of the drive, offering a consistent pace. While not a winding, scenic byway, the efficiency of the interstate system allows for smooth and direct travel between Clayton and Winston-Salem. The character is largely about covering distance effectively on well-maintained roads.

Most of the miles stay on highways, which makes pacing and fuel planning easier than turn-by-turn city driving.
There are about 16 navigation steps in the underlying route data, so the final approach matters more than the middle miles.
Dan K Moore Freeway is the longest continuous segment at about 69.7 miles.

How Hard Is This Drive?

This is a straightforward highway drive that stays mostly on Dan K Moore Freeway and I 40. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 0.5 miles in near Barbour Street.

Driving Effort 7/10

Demanding - plan breaks and stay ahead of the key maneuvers

Balances navigation complexity with total wheel time.

This is a demanding drive. With 9 significant decision points across 120.6 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.

Where does it get tricky?

The main spots that need attention: at 0.5 miles (Barbour Street): Navigation decision point; at 86.3 miles (I 40): Highway fork - watch signs carefully. Lane positioning matters here; at 94 miles (I 40; US 220): Highway fork - watch signs carefully. Lane positioning matters here.

Critical Maneuvers

5 of 9 key points

These are the spots where you need to pay the most attention. Preview them before you drive.

5
0.5 mi into trip | ~1m in | Barbour Street

Turn left onto Barbour Street

Navigation decision point

6
86.3 mi into trip | ~1h 43m in | I 40

Keep slight right at fork onto I 40

Highway fork - watch signs carefully. Lane positioning matters here

Use the straight / slight left lanes.
6
94 mi into trip | ~1h 53m in | I 40; US 220

Keep slight right at fork onto I 40; US 220

Highway fork - watch signs carefully. Lane positioning matters here

Use the straight lane.
8
106.6 mi into trip | ~2h 8m in | US 421 / Salem Parkway

Keep slight right at fork onto US 421 / Salem Parkway toward US 421 North: Kernersville

Highway fork - watch signs carefully. Lane positioning matters here

Use the straight lane. Exit 206 Toward US 421 North: Kernersville
7
120 mi into trip | ~2h 24m in

Take the exit toward Main Street

Exit ramp - move to the correct lane early. Lane positioning matters here

Use the slight right lane. Exit 233A Toward Main Street

Main Roads

Road Distance Duration
Dan K Moore Freeway 69.7 mi 1h 20m
I 40 20.3 mi 24m
Salem Parkway 13.4 mi 16m
Thomas Bradshaw Freeway 8.5 mi 9m
US 70 4.3 mi 5m
Clayton Boulevard 2.4 mi 3m
South Main Street 0.4 mi <1m
North Lombard Street 0.4 mi 1m
Longest stretch: Dan K Moore Freeway — 69.7 mi, about 1h 20m

Turn-by-Turn Driving Directions

Step-by-step road directions between Clayton, NC and Winston-Salem, NC.

1

Start on North Lombard Street

0.4 mi · 1 min · North Lombard Street
2

Turn right onto Hamby Street

427 ft · 15 sec · Hamby Street
3

Turn left onto Barbour Street

0.2 mi · 33 sec · Barbour Street
4

Turn straight onto US 70

2.4 mi · 3 min · Clayton Boulevard
5

Continue on US 70

4.3 mi · 5 min · US 70
6

Take the ramp

0.8 mi · 1 min
Toward I 40 West: Raleigh
7

Merge onto I 40

7.4 mi · 8 min · Thomas Bradshaw Freeway
Use the straight / slight right lanes.
8

Continue on I 40; US 64

2.7 mi · 3 min · Dan K Moore Freeway
9

Continue on I 40; US 64

1.1 mi · 1 min · Thomas Bradshaw Freeway
10

Continue on I 40; US 64

67 mi · 1 hr 17 min · Dan K Moore Freeway
Use the straight lane.
11

Keep slight right at fork onto I 40

7.7 mi · 9 min · I 40
Use the straight / slight left lanes.
12

Keep slight right at fork onto I 40; US 220

13 mi · 15 min · I 40; US 220
Use the straight lane.
13

Keep slight right at fork onto US 421

13 mi · 16 min · Salem Parkway
Exit 206 Toward US 421 North: Kernersville Use the straight lane.
14

Take the exit

0.2 mi · 28 sec
Exit 233A Toward Main Street Use the slight right lane.
15

Turn slight right onto South Main Street

0.4 mi · 44 sec · South Main Street
Use the straight lane.
16

Arrive at destination

North Main Street

Trip Plan

Given the 2 hour and 25-minute duration and 120.6-mile distance, this trip is best suited for a single day, with no need to split it. Consider an early morning departure to avoid any potential traffic, especially as you approach Winston-Salem. While there are no designated stops in the data, plan for a brief break around the halfway point to stretch your legs. Keep an eye on your fuel; the estimated cost is $19, so you should have ample range, but it's always wise to top off before embarking. A specific tip for this route: be aware that the Dan K Moore Freeway eventually merges into I-40, so stay alert for lane changes as you transition.

Morning Departure

Leave by 9 AM and you'll arrive before lunch.

Evening Departure

Even a 4 PM departure gets you there before dark in summer.

You can normally do this drive in one day.
You may only need one short stretch break if traffic stays light.
The halfway point lands around 60.3 miles from Clayton, NC, or about 1h 13m into the drive.
The longest continuous stretch on this route runs about 69.7 miles.

This is a comfortable same-day trip.

Departure

Before you leave

Start with fuel, water, and navigation already sorted so the first hour feels easy.

First stop

Around 27 miles or 35m in

Use this first pause for coffee, a restroom break, and a quick traffic check ahead.

Halfway reset

Around 60.3 miles or 1h 13m in

This is the best place for your longest stop, a real meal, and a full fuel check.

Final approach

Final hour starts around 1h 59m

Traffic, exits, and arrival timing usually matter more near Winston-Salem, NC than in the middle of the route.

Before You Leave

+

Open the route before leaving Clayton, NC so your first major turns are already loaded.

+

Leave with enough water and a charging cable within reach, not packed away.

+

Check your fuel range against the first long segment, especially if you are starting outside city service areas.

Day 1

Settle into the route from Clayton, NC

This is one driving day of about 120.6 miles and 2h 25m.

Your first comfortable stop window is around 27 miles from Clayton, NC.
This route can stay practical as a one-day drive if traffic stays reasonable.
The longest stretch is on Dan K Moore Freeway for about 69.7 miles.

Where to Stop

Rest stops, refuel points, and overnight suggestions along this route.

Halfway Point

Midpoint

About 60.3 mi from Clayton, NC · 1h 13m into the drive

town in and county seat of Orange County, North Carolina, United States

Mid-route town

Meal stop

Hillsborough, NC

60 mi into the route

Best for: Lunch, fuel, and a longer reset

This sits close to the middle of the route, so it works well for the longest stop of the day.

Pacing Suggestions

Cary, NC

Fuel and coffee

A short stop after about 27 miles helps settle the day before fatigue starts building.

Hillsborough, NC

Meal break

The midpoint is around 60.3 miles from Clayton, NC, which is a good place for a longer meal and fuel stop.

Before the longest stretch

Fuel check

Top up before Dan K Moore Freeway if your tank is already low. That segment runs about 69.7 miles.

Arriving in Winston-Salem, NC

The final approach into Winston-Salem, NC usually feels slower than the middle of the drive, so avoid planning your tightest schedule at the very end.

Try to arrive with enough fuel left to skip an immediate station stop unless you already know the area around Winston-Salem, NC.

These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.

Fuel & Cost

Regular Gas

$18.86 one way

$37.72 round trip

$3.97/gal 25.4 MPG avg 42 kg CO2
Fuel Type $/gal One Way Round Trip
midgrade $4.34 $20.62 $41.24
premium $4.70 $22.32 $44.64
diesel $5.61 $26.63 $53.25

No toll roads detected on this route.

Estimated Trip Cost (one way, 1 person)

Fuel

$19

Meals

$25–$50

Total

$44–$69

Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.

Estimated CO2 emission: 42.2 kg one way. Prices: EIA weekly data, 2026-04-13.

Driving Electric?

About $13 in charging · 0 stops · 67% less CO2

Vehicle Type kWh Stops DC Fast Home Charge
Average EV 36.2 0 $12.66 $5.79
Efficient EV 30.2 0 $10.55 $4.82
EV Truck/SUV 48.2 0 $16.88 $7.72

Gas CO2

42 kg

EV CO2

14 kg (67% less)

This trip is well within single-charge range for most EVs. No charging stops needed if you start fully charged.

DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.

Travel Intel

Current conditions at both ends of the drive.

Forecast as of Apr 15, 2026

Origin

Clayton, NC

Night in Clayton on Thursday

Local time

11:57 PM

EDT

Current temp

49°F

Unavailable

Live forecast

Destination

Winston-Salem, NC

Night in Winston-Salem on Thursday

Local time

11:57 PM

EDT

Current temp

42°F

Unavailable

Live forecast

50°F

Hillsborough, NC

60 mi in

Seasonal Notes

Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.

Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.

Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.

Time zone

Same local time

Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.

Temperature spread

7 degrees cooler at arrival

A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.

Road read

2h 25m on the road

Use the two city cards together: check the sky where you start, then compare it with the local time and temperature at arrival.

Weather data from the National Weather Service. Conditions may change; check closer to your travel date.

Frequently Asked Questions

The drive from Clayton, NC to Winston-Salem, NC covers 120.6 miles and takes about 2h 25m without stops. Add 15-30 minutes for a fuel or rest stop on longer drives.
The main roads are Dan K Moore Freeway, I 40, Salem Parkway. Most of the drive stays on highways, so watch for ramps and exits.
This is a comfortable same-day trip.
The midpoint is about 60.3 miles from Clayton, NC. Look for rest areas, gas stations, or food options near the halfway mark.
At current regular gas prices, expect to spend about $18.86 one way. This estimate uses 25.4 MPG — your actual cost will vary with your vehicle's fuel efficiency and current gas prices.
Leave by 9 AM and you'll arrive before lunch. Even a 4 PM departure gets you there before dark in summer.
This is a demanding drive. With 9 significant decision points across 120.6 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
The main spots that need attention: at 0.5 miles (Barbour Street): Navigation decision point; at 86.3 miles (I 40): Highway fork - watch signs carefully. Lane positioning matters here; at 94 miles (I 40; US 220): Highway fork - watch signs carefully. Lane positioning matters here.
The route from Clayton, NC to Winston-Salem, NC does not surface many named destination signs beyond the main corridor.

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