Origin
Joplin, MO
Evening in Joplin on Wednesday
Local time
6:34 PM
CDT
Current temp
57°F
Unavailable
Live forecast
Trip from Joplin, MO to Perryville, MO
Last recalculated Apr 15, 2026
Drive Time
6h 20m
Distance
326.9 mi
526 km
Drive Score
8/10
Great drive
Same Day?
Yes, doable
Fuel Cost
$51
one way
Best Time to Leave
4 AM
6h 7m
★
6 AM
6h 20m
8 AM
6h 45m
10 AM
6h 29m
12 PM
6h 26m
3 PM
6h 30m
5 PM
6h 44m
8 PM
6h 12m
Estimated drive times based on typical traffic patterns. Actual times may vary with weather, construction, and real-time conditions.
Joplin, MO
Wikimedia Commons
Perryville, MO
Wikimedia Commons
Trip Overview
The drive from Joplin, MO to Perryville, MO covers 326.9 miles and takes about 6h 20m behind the wheel. This route is realistic as a one-day drive if you keep your stops efficient.
The route leans on East 7th Street, Cimarron Road, I 44 East for much of the mileage, and the overall profile is turn-heavy local drive. At current regular gas prices, budget about $51.11 one way before food or hotel costs.
Trip Pace
Same-day drive is realistic
A same-day return is possible, but it will make for a full day on the road.
Break Rhythm
1 planned break
Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
Midpoint
163.4 miles from Joplin, MO
A natural place for your longest stop of the day , about 3h 10m into the drive .
Drive Character
Expect a 6h 20m drive with frequent turns across 326.9 miles of local and secondary roads.
This route has more turning and local-road decision points than a simple highway run.
There are about 25 navigation steps in the underlying route data, so the final approach matters more than the middle miles.
East 7th Street is one of the defining roads on this drive.
How Hard Is This Drive?
Expect a hands-on drive with frequent turns and local roads rather than long highway stretches. There are only a few real navigation decisions along the way.
Route Complexity
3/10
Easy - simple navigation with a manageable amount of wheel time
The route itself is not hard, but at 6h 20m, endurance matters. Plan breaks every 2-3 hours. The 0 decision points are all manageable with basic attention.
Where does it get tricky?
This route does not have any notably tricky sections. Most of the drive from Joplin, MO to Perryville, MO is straightforward, with well-signed roads and simple exits.
Main Roads
| Road | Distance | Duration |
|---|---|---|
| East 7th Street | — | — |
| Cimarron Road | — | — |
| I 44 East | — | — |
| Congressman Gene Taylor Highway | — | — |
| MO 30 | — | — |
| West Gravois Avenue | — | — |
| East Gravois Avenue | — | — |
| Metropolitan Boulevard | — | — |
Some road-level metrics are being recalculated.
Longest stretch:
East 7th Street
— detailed segment metrics are refreshing.
Turn-by-Turn Driving Directions
Step-by-step road directions between Joplin, MO and Perryville, MO.
1
Start on the route
220 ft
·
18 sec
·
the route
2
At the end of the road, turn right
194 ft
·
19 sec
3
Turn left onto East 7th Street
6.8 mi
·
14 min
·
East 7th Street
4
Continue on Cimarron Road
0.9 mi
·
1 min
·
Cimarron Road
5
Take the ramp slight right toward I 44 East, I 49 North, US 71 North: Springfield, Kansas City
0.6 mi
·
1 min
·
I 44 East, I 49 North, US 71 North: Springfield, Kansas City
6
Merge slight left onto Congressman Gene Taylor Highway
223 mi
·
4 hr 1 min
·
Congressman Gene Taylor Highway
7
Take the exit slight right toward MO WW, MO AB, MO 30: Saint Clair
0.2 mi
·
23 sec
·
MO WW, MO AB, MO 30: Saint Clair
8
Turn right
0.1 mi
·
22 sec
9
Continue on West Gravois Avenue
0.2 mi
·
25 sec
·
West Gravois Avenue
10
Take the exit slight right toward MO 30, MO 47
190 ft
·
5 sec
·
MO 30, MO 47
11
Merge slight left onto East Gravois Avenue
27 mi
·
38 min
·
East Gravois Avenue
12
Turn right
12 mi
·
17 min
13
Take the exit slight right
180 ft
·
5 sec
14
Turn right onto Metropolitan Boulevard
0.1 mi
·
15 sec
·
Metropolitan Boulevard
15
Enter the roundabout and take exit 3 toward I 55 South: Cape Girardeau
217 ft
·
10 sec
·
I 55 South: Cape Girardeau
16
Exit the roundabout onto I 55 South: Cape Girardeau
0.2 mi
·
10 sec
·
I 55 South: Cape Girardeau
17
Merge slight left onto Jeff McBride Memorial Highway
49 mi
·
52 min
·
Jeff McBride Memorial Highway
18
Take the exit slight right toward MO M: Brewer
0.2 mi
·
29 sec
·
MO M: Brewer
19
Turn left
0.6 mi
·
1 min
20
At the end of the road, turn right
5.3 mi
·
7 min
21
Enter the roundabout and take exit 1 toward North Main Street
56 ft
·
1 sec
·
North Main Street
22
Exit the roundabout onto North Main Street
0.5 mi
·
1 min
·
North Main Street
23
Turn left onto East Saint Joseph Street
364 ft
·
18 sec
·
East Saint Joseph Street
24
Turn right onto South Spring Street
220 ft
·
10 sec
·
South Spring Street
25
Arrive at your destination
Trip Plan
Morning Departure
Start early — leave by 6-7 AM to arrive at a reasonable hour.
Evening Departure
This is a long drive — plan for a morning departure or consider splitting it into two days.
You can normally do this drive in one day.
Plan roughly 1 meaningful break for fuel, food, and rest.
The halfway point lands around 163.4 miles from Joplin, MO, or about 3h 10m into the drive.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 72 miles or 1h 23m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 163.4 miles or 3h 10m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 5h 11m
Traffic, exits, and arrival timing usually matter more near Perryville, MO than in the middle of the route.
Before You Leave
+
Open the route before leaving Joplin, MO so your first major turns are already loaded.
+
Leave with enough water and a charging cable within reach, not packed away.
+
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from Joplin, MO
This is one driving day of about 326.9 miles and 6h 20m.
Your first comfortable stop window is around 72 miles from Joplin, MO.
This route can stay practical as a one-day drive if traffic stays reasonable.
Plan about 1 real break rather than only quick fuel stops.
Where to Stop
Rest stops, refuel points, and overnight suggestions along this route.
Halfway Point
Midpoint
About 163.4 mi from Joplin, MO · 3h 10m into the drive
Mid-route town
Meal stop
163 mi into the route
Best for: Lunch, fuel, and a longer reset
This sits close to the middle of the route, so it works well for the longest stop of the day.
Pacing Suggestions
Fuel and coffee
A short stop after about 72 miles helps settle the day before fatigue starts building.
Meal break
The midpoint is around 163.4 miles from Joplin, MO, which is a good place for a longer meal and fuel stop.
Arriving in Perryville, MO
The final approach into Perryville, MO usually feels slower than the middle of the drive, so avoid planning your tightest schedule at the very end.
Try to arrive with enough fuel left to skip an immediate station stop unless you already know the area around Perryville, MO.
These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.
Fuel & Cost
Regular Gas
$51.11 one way
$102.21 round trip
$3.97/gal
25.4 MPG avg
114 kg CO2
| Fuel Type | $/gal | One Way | Round Trip |
|---|---|---|---|
| midgrade | $4.36 | $56.11 | $112.23 |
| premium | $4.89 | $62.91 | $125.82 |
| diesel | $5.61 | $72.18 | $144.35 |
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$51
Meals
$25–$50
Total
$76–$101
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 114.4 kg one way. Prices: EIA weekly data, 2026-04-13.
Driving Electric?
About $34 in charging · 1 stop · 67% less CO2
| Vehicle Type | kWh | Stops | DC Fast | Home Charge |
|---|---|---|---|---|
| Average EV | 98.1 | 1 | $34.32 | $15.69 |
| Efficient EV | 81.7 | 0 | $28.60 | $13.08 |
| EV Truck/SUV | 130.8 | 1 | $45.77 | $20.92 |
Gas CO2
114 kg
EV CO2
38 kg (67% less)
Plan for 1 charging stop. A 30-minute DC fast charge mid-route should be enough to complete the trip comfortably.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive.
Destination
Perryville, MO
Evening in Perryville on Wednesday
Local time
6:34 PM
CDT
Current temp
56°F
Unavailable
Live forecast
57°F
Chesterfield, MO
163 mi in
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Same local time
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
1 degrees cooler at arrival
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
6h 20m on the road
Start early — leave by 6-7 AM to arrive at a reasonable hour.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
Frequently Asked Questions
The drive from Joplin, MO to Perryville, MO covers 326.9 miles and takes about 6h 20m without stops. Add 15-30 minutes for a fuel or rest stop on longer drives.
The main roads are East 7th Street, Cimarron Road, I 44 East. Expect a mix of highway and local road driving.
This is a comfortable same-day trip.
The midpoint is about 163.4 miles from Joplin, MO. Look for rest areas, gas stations, or food options near the halfway mark.
At current regular gas prices, expect to spend about $51.11 one way. This estimate uses 25.4 MPG — your actual cost will vary with your vehicle's fuel efficiency and current gas prices.
Start early — leave by 6-7 AM to arrive at a reasonable hour. This is a long drive — plan for a morning departure or consider splitting it into two days.
Plan about 1 meaningful break for fuel, food, or rest. Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
The route itself is not hard, but at 6h 20m, endurance matters. Plan breaks every 2-3 hours. The 0 decision points are all manageable with basic attention.
This route does not have any notably tricky sections. Most of the drive from Joplin, MO to Perryville, MO is straightforward, with well-signed roads and simple exits.
The route from Joplin, MO to Perryville, MO does not surface many named destination signs beyond the main corridor.
Was this route helpful?
Thanks for your feedback!
Your tip has been submitted. Thanks!
/500
Recent Tips
·
Explore More
Continue From Perryville, MO
More trips to Perryville, MO
Explore more options from Joplin, MO or browse trips ending in Perryville, MO.
Looking for more statewide routes? Browse MO road trips.
Explore maps for Joplin, MO or Perryville, MO on MapSof.net.